This transgene expresses a cre recombinase/ mutant estrogen receptor ligand-binding domain fusion protein under the control of a mouse cardiac-specific alpha-myosin heavy chain promoter. The protein is inactive until induced with tamoxifen. On a C57BL/6 background, the inducible cre expression is higher than that of a similar transgene on a 129/Sv background. The protein is inactive until induced with tamoxifen. (J:109582)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count