The transgene expresses the carboxy-terminal proteolytic fragment (p25) of human cyclin-dependent kinase 5, regulatory subunit 1, bearing a carboxy-terminal green fluorescent protein (GFP) tag, under control of the tetracycline operator. The purpose of the GFP tag is to differentiate immunologically the transgene-encoded p25 from the endogenous p35 protein. (J:104240)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count