Bay Genomics gene trap vector pGt1Lxf was randomly inserted 11kb downstream of exon 3 in intron 3 which is 75 kb in size. RNA for the wild-type allele was detected in the brain by RT-PCR along with a larger band in mice carrying the gene trap allele and lacking the wild-type allele (J:111316). An independent report indicated that this allele is hypomorphic and that residual low-level expression of a properly spliced transcript is found in homozygous mice (J:114758). (J:111316)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
3
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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