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EN
A single loxP sites was inserted just 5' of exon 4. Then an Frt flanked neomycin selection cassette followed by a second loxP site was inserted 3' of exon 4. Mice containing this targeted mutation were then crossed with transgenic mice expressing Flp recombinase under the control of beta Actin. Exon 4 is flanked by loxP sites in the resulting mice. (J:111316)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
