An Igh-V12 fragment derived from the PtC-specific lymphoma cell line CH27 was fused to the 5' end of the IgM constant region gene. Four founder lines were established and two of them were characterized. Line 6-1 contains 15-20 copies of the transgene and line 7-2 contains 1-2 copies. (J:111246)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count