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A targeting vector was designed to insert loxP sites to flank exons 12 through 21 of the locus. Frt sites flanked a neo included in the vector in intron 11. The floxed locus encompasses the ATPase domain, required for the remodeling activity. Splicing of exon 11 to exon 22 would putatively generate an out of frame transcript, possibly resulting in a truncated protein. (J:109547)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
