This transgene consists of SV40 small T antigen in a reverse orientation, a 900 bp fragment of the Amy2 promoter region, cre recombinase, and a human growth hormone mini gene. Cre expression is seen in the definitive endoderm starting at E9.0 but is not seen in the liver or ventral pancreas before E12.5. The integration site was mapped to chromosome 15 in the promoter region of Zhx1. (J:110139)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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Insertion
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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