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The transgene comprises the node-specific enhancer (NDE), which in the mouse genome resides in a 0.8-kb region 9.5-8.7 kb upstream of the Nodal coding sequence, followed by nucleotides -664 through +113 of the mouse heat shock protein 1B genomic sequence, a fusion gene combining the coding sequences of the E. coli genes gpt, TrpS and lacZ, and an SV40 polyadenylation signal. (J:83358)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
