A loxP flanked neo cassette was inserted into intron 21 and a single loxP site was inserted into intron 22. The neo cassette was then removed Cre mediated recombination leaving a floxed exon 22. (J:110200)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count