In an ES cell line in which a loxP site previously had been inserted into the Es2el gene by homologous recombination, a second loxP site was inserted into the T10 gene using a retrovirus. Transient cre-expression in the ES cells resulted in deletion of a 500-kb region from Es2el to T10. (J:67409)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Intergenic deletion, Intragenic deletion
--
--
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top