A targeting vector with the Hprt delta5' cassette and a loxP site was used to replace a 4.5kb region containing exons 2-3 of Ufd1l. The Udf1ltm1Bld mutant allele was created in the double-targeted cell line 217 which was originally derived from AB2.2 ES cells J:57757. (J:57757)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count