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An 800kb deletion including the last 8 exons of Uchl3 and the entire Lmo7 gene was created using Cre-loxP recombination in ES cells to insert loxP sites at the breakpoints of the intended deletion. Targeting vectors were injected into AB2.2 ES cells and correctly targeted clones were electroporated with a Cre-expressing plasmid to excise the 800kb region. (J:83810)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
