This transgene contains the murine Fosl1 gene fused to the major histocompatibility complex class I antigen H2-Kb promoter. To stabilize the Fosl1 mRNA and ensure expression in mesenchymal cells, the 3' long terminal repeat sequence of the FBJ-murine sarcoma virus was linked to the 3' end of the Fosl1 gene. Fosl1 mRNA is widely expressed in various organs, including bone. (J:64494)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F1
--
Insertion
--
1
--
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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