The human GPHB5 open reading frame was inserted into a vector containing the metallothionein-1 promoter and a consensus translation initiation sequence was placed upstream of the GPHB5 ATG. Introns from the rat INS2 and a human GH polyadenlyation signal sequence were cloned 5' and 3' of GPHB5 to enhance transcription. (J:105176)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F1
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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