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This transgene contains the full length cDNA of rat Prkaa2 with the lysine at residue 45 (residue critical for ATP binding and hydrolysis) changed to arginine and tagged at the 5'end with a myc epitope under the control of the muscle creatine kinase promoter. Expression of endogenous Prkaa2 is completely undetectable and transgene expression occurs in skeletal and cardiac muscle. (J:110092)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
