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This transgene expresses a constitutively active mutant of Akt1 (the Akt1 cDNA contains a Src myristoylation signal) under the control of the mouse alpha-myosin heavy chain promoter. This transgene integrated on the X chromosome and its expression is greater in males than females. (J:77257)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
