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This transgene consists of the human insulin-like growth factor 1B cDNA under the control of the rat alpha-myosin heavy chain promoter. IGF1 mRNA was not detectable in the fetal heart at the end of gestation but is present at modest levels at 1 day after birth and increased progressively with postnatal maturation, reaching a peak at 75 days. IGF1 is exclusively expressed in the heart. (J:35215)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
