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A targeting vector was designed to flank the sonic hedgehog processing domain in exon 3 with loxP sites. The second loxP site was followed by a Myc epitope tag with a stop codon and an FRT site flanked neomycin resistance gene cassette downstream of the stop codon. The neo cassette was removed by crossing with mice expressing flp recombinase. (J:109101)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
