A targeting vector was designed to mutate the EKKY in the second intracellular loop to DSEL. A neomycin gene inserted into the intron between exons E1 and E2 was subsequently removed via transient cre expression. (J:108984)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count