The insertion of the VICTR48 vector into intron 1 resulted in the splicing of 5' exonic sequences to a neomycin resistance cassette. The vector contained long terminal repeats, neo-pA, BTK and additional LTR sequence. The final product was a fusion of exon 1 and the neo. Protein expression was not detected in mutant embryos. (J:109220)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
Insertion of gene trap vector
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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