A targeting vector was designed to insert a D823G substitution. Cre mediated recombination removed a floxed IRES-betageo from the locus. This allele produced protein at levels similar to those of wild-type mice. (J:106540)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count