A truncated gene was created by the in frame insertion of a neomycin resistance cassette into exon 16 at amino acid 1358. Northern blot detected a longer transcript than wild-type, indicating the correct insertion of the neo. Western blot failed to detect a Myst3-neo fusion protein in mutants. (J:108453)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
4
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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