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The mouse Mt1 minimal promoter was used to drive expression of a human STC1 construct made up of a genomic fragment containing 93bp of the 5' UTR, exon 1, intron 1, exon 2, and intron 2. This was fused to a human cDNA containing exon 3 and 573 bp of exon 4. The remainder of the construct was made up of 800 bp from the 3' UTR of the human GH gene. Line 1A contains approximately 10 copies of the transgene. (J:109144)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
