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A neomycin resistance cassette replaced the coding sequence. RC-PCR analysis did not detect mRNA in brain, skeletal muscle, and skin tissue from homozygous mutant mice. Immunohistochemical studies of frontal sections from brain did not detect protein in the locus ceruleus of homozygous mutant mice. (J:108744, J:116101)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
