Variable germline expression of cre disrupted the targeted allele carrying floxed exon 2 resulting in removal of exon 2 in some gonadal cells, instead of the expected tissue-specific disruption of the floxed allele by the Camk2a-cre transgene. (J:104338)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count