This is a large inversion on Chromosome 4 which arose in a DBA/2J male exposed to 1000R of radiation. It covers most of chromosome 4 with the breakpoints in G bands 4A1 and 4E2. The distal breakpoint of the inversion is in the second intron of the Gnb1 gene and the proximal breakpoint lies within the centromere. (J:41514, J:108450)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(DBA/2J x C57BL/6J)F1
Radiation induced
Intragenic deletion, Inversion
Semidominant
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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