Exon 10, which encodes most of the hydrophilic loop, was removed from the locus via cre-mediated recombination. Western blot detected a truncated C-terminal fragment due to the deletion of the exon. (J:107251)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count