The region from 550 base pairs upstream of the putative promoter to 240 base pairs downstream of the exon 1/intron 1 junction was replaced with a cassette encoding the a tet-responsive promoter that directs expression of Ednrb cDNA. Also included in the vector is a floxed hygromycin resistance gene. (J:58698)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count