A floxed neo cassette and a single loxP site flanking exons 2 and 3 were introduced via homologous recombination. The floxed neo cassette was removed by transient expression of cre recombinase in correctly targeted cells leaving exons 2 and 3 flanked by loxP sites. (J:81398)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count