A fragment of human RUNX1 cDNA containing 62 bp of exon 4 and the rest of the coding region was inserted in-frame into the mouse exon 4. IRES sequences were included upstream of both the MN1-TEL (type 1) and the GFP cDNAs. A stop sequence flanked by loxP sites was located between the RUNX1 and IRES-MN1-TEL cDNAs. (J:106800)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count