Runx1^{tm1(RUNX1)Gcg}

A fragment of human RUNX1 cDNA containing 62 bp of exon 4 and the rest of the coding region was inserted in-frame into the mouse exon 4. IRES sequences were included upstream of both the MN1-TEL (type 1) and the GFP cDNAs. A stop sequence flanked by loxP sites was located between the RUNX1 and IRES-MN1-TEL cDNAs. (J:106800)