A fragment of human RUNX1 cDNA containing 62 bp of exon 4 and the rest of the coding region was inserted in-frame into the mouse exon 4. IRES sequences were included upstream of both the MN1-TEL (type 1) and the GFP cDNAs. A stop sequence flanked by loxP sites was located between the RUNX1 and IRES-MN1-TEL cDNAs. (J:106800)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion
--
1
8
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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