Log In|Sign Up
EN
A cassette containing a single-chain reverse tetracycline-controlled trans-silencer (sc rtTS), a tetracycline-controlled transactivator (tTA), and a tetracycline responsive element (TRE) were introduced upstream of the translation start site in exon 2. The sc rtTS consists of two silencer moieties connected via a 36 amino acid linker. In the presence of doxycycline, the sc rtTS binds to tetO to suppress leaky expression of the locus. (J:104881, J:106458)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
