Exon 4 was flanked by loxP sites via homologous recombination. Exon 4 is the first allele common to all splice variants. Cre-mediated excision of exon 4 was accomplished by breeding to a Cre-expressing line. (J:105920)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count