A targeting vector was used to change an NFD amino acid sequence beginning at residue 893 to EIG (NFD893-895EIG), which disables the protein's ability to interact with Dab1. GST pull-down experiments confirmed the disruption of this interaction. (J:105699)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count