A targeting vector was designed to insert an S2808A mutation into exon 55 by homologous recombination. A self-excising Cre recombinase with a testes-specific promoter, was removed from the locus upon passage through the germline. (J:105666)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count