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This allele was generated by crossing mice bearing Sfpi1tm1Dgt with mice ubiquitously expressing FLP recombinase to produce progeny in which the FRT-flanked PGKneo cassette has been deleted. This leaves a single FRT site immediately upstream of the 5' member of a pair of loxP sites flanking the 3.4-kb upstream regulatory element (URE) that is located 14 kb upstream of the endogenous gene. Expression of the protein is unaffected by presence of the FRT or loxP sites. (J:90331, J:106788)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
