This mutation was generated by cre-mediated deletion of both exon 5 and the neomycin selection cassette from the floxed Vezttm1Smc allele. Presence of the same two major bands on immunoblots of brain and testis protein extracts from wild-type and heterozygous mutant mice indicates absence of a protein product from the mutant allele; these bands are twice as intense for wild-type as for mutant samples. (J:121686)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Intragenic deletion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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