The bm13 mutation consists of four nucleotide changes that result in amino acid changes in codons 114 (leucine to glycine), 116 (phenylalanine to tyrosine) and 119 (glutamate to aspartate). A mutation in codon 118 is silent. The mutation is thought to have arisen by a gene conversion event with the H-2Kb acting as the donor locus. (J:106337)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6ByKh x BALB/cByKh)F1
Spontaneous
Nucleotide substitutions
--
1
12
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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