LoxP sites were inserted to flank promoter sequences, exons 1 and 2. The frt flanked neo cassette was removed by flp mediated recombination. Deletion of this sequence would remove the start codon, the 5' SNAG repression domain and the first three zinc finger DNA binding domains of the protein. (J:105294)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion
--
1
--
19

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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