ES cells containing the Kpnb1Gt(pU-hachi)1Arak allele were targeted with a cre plasmid and a vector containing Kpnb1 cDNA, resulting in the replacement of the IRES-betageo within the gene trap vector with Kpnb1 cDNA, and PGK-puro. Mutants expressed both the endogenous and inserted sequences. (J:105350)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count