A Ptch1 cDNA from which the 5'UTR and 3'UTR were removed was cloned into an expression vector containing the mouse metallothionein I promoter. Two of four lines were maintained. This line has a higher transgene copy number and a stronger phenotype than the other. (J:56195)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count