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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Gphb5
tm1Lex
Alias:
GPHB5-
GPB5
-
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Basic Information
Phenotypes
References Literature
A 179-bp genomic region at exon 3 of the Gphb5 gene was deleted by a replacement-type vector with 10-kb homology arms. Thus, approximately half the open reading frame of Gphb5 was deleted and replace with an IRESLacZ/MC1-Neo selection cassette.
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3615364
129S5/SvEvBrd
Targeted
Insertion, Intragenic deletion
--
1
--
4
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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