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Velocigene technology was used to insert a cassette containing a lacZ-stop-PGK-noe-stop cassette immediately downstream of the ATG in exon 2, subsequently replacing the rest of exon 2 and all of exon 3. Western blot did not detect protein in mutant sciatic nerve lysates. Beta-gal expression was detected widely in the E15 mouse embryo. (J:104989)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
