The transgene construct was composed of a 2.2 kb genomic clone of the human gene and contained 256 bp of 5' sequence. Ten to 50 copies were inserted. The human gene is expressed in liver but not in intestine, testis, or ovary. Average human APOA-I levels are 339mg/dl. (J:94253)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x CBA/J)F1
--
Insertion
--
1
--
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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