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The exons 9 and 10, encoding the C-terminal portion of the DNA-binding domain and flanked by loxP sites, were removed after crossing with mice expressing cre in an epiblast-restricted manner allowing targeted recombination in all adult tissues. PCR showed that less than 10-15% of the functional Ets2tm3Rgo allele remained in adult tissues. Mammary tissue was nearly completely recombined. (J:102368)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
