The genomic region encoding the secretion signal and part of the first Ig-domain were replaced with a lacZ and neo cassette. LacZ expression was detected in the accessory olfactory bulb, anterodorsal thalamic nuclei, inferior colliculi, layer 5 of the cerebral cortex and the cerebellum. Western blot failed to detect protein in mutant brains. (J:61081, J:104862)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count