The genomic region encoding the secretion signal and part of the first Ig-domain were replaced with a lacZ and neo cassette. LacZ expression was detected in the accessory olfactory bulb, anterodorsal thalamic nuclei, inferior colliculi, layer 5 of the cerebral cortex and the cerebellum. Western blot failed to detect protein in mutant brains. (J:61081, J:104862)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
Insertion, Intragenic deletion
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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