The cDNA for human ADORA3, encompassing sequence from the ATG to the TAG stop codon, was inserted into exon 1 at the ATG. RT-PCR analysis detected human transcript at the same levels and with the same distribution as endogenous transcript in wild-type mice. No expression of the mouse transcript was detected in mutant mice. (J:104494, J:104495)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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