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The transgene comprises approximately 80 copies of the genome of the shuttle vector lambda EG10, which is composed of the genome of phage lambda2001 joined to a linearized plasmid. Lambda2001 contains, in addition to the genes necessary for infectivity, a chi site and the red and gam genes that together confer sensitivity to P2 interference. The plasmid portion of EG10 contains two loxP sites and the E. coli chloramphenicol resistance (CamR) and xanthine-guanine phosphoribosyl transferase (gpt) genes. (J:104540)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
