Exons 3-5 were replaced by a neomycin resistance cassette flanked by two loxP sites and the neo cassette was subsequently removed with cre recombinase. Northern blot failed to detect transcript in mutant pulmonary microvessel endothelial cells. Protein was not detected by immunological assay. (J:104459)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count