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An inverted mc1 promoter-driven neo flanked by two loxP sites was inserted into intron 34. A third loxP site was inserted into intron 30. RT-PCR detected a faint band. Wesetern blot detected a faint baind corresponding to amino acids 866-882. These analyses indicated that the insertion causes a significant disturbance but does not completely abrogate expresson of the gene. (J:104361)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
