A targeting vector was designed to replace exon 1, containing the ATG start codon, with a neomycin resistance gene flanked by loxP sites. Transcript was not detected in mutant kidney, intestine, brain, lung or liver samples by RT-PCR. (J:104101)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count